Caenorhabditis elegans Flamingo Cadherin fmi-1 Regulates GABAergic Neuronal Development
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منابع مشابه
Caenorhabditis elegans flamingo cadherin fmi-1 regulates GABAergic neuronal development.
In a genetic screen for regulators of synaptic morphology, we identified the single Caenorhabditis elegans flamingo-like cadherin fmi-1. The fmi-1 mutants exhibit defective axon pathfinding, reduced synapse number, aberrant synapse size and morphology, as well as an abnormal accumulation of synaptic vesicles at nonsynaptic regions. Although FMI-1 is primarily expressed in the nervous system, it...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2012
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.3094-11.2012